Cannabidiol CBD has many therapeutic and medical benefits that are useful in the treatment of a wide variety of ailments, including serious or complex conditions like stage 4 cancer and seizures. Among them, its effectiveness in the treatment of epileptic seizures has been proven in multiple clinical and scientific studies. Studies have shown that CBD oil for grand mal seizures is effective due to cannabidiol’s neuroprotective effect coupled with anticonvulsant effect. The purpose of this primer is to get a better understanding about this topic, read on to know more.
What Is Grand Mal Seizure?
Grand Mal seizures which is also known as tonic-clonic seizures is characterised by loss of consciousness followed by violent muscle contractions. It is due to abnormally high electrical activity in the neurons caused by epilepsy. It can also be caused by other health conditions like low blood sugar, stroke or even high fever. It has two phases, namely the tonic phase and the clonic phase. In the tonic phase, the person loses consciousness along with muscle contraction and as result the person falls or collapses. In the clonic phase, muscles go into convulsions i.e. they alternatively flex and relax. The first phase lasts for about 10 to 20 seconds and the second phase lasts for about 1 to 2 minutes or less.
How Is CBD For Epilepsy Useful In Grand Mal Seizures?
The goal of any antiepileptic medication is the reduction of the number of seizures and there are cases of drug resistant epilepsy. CBD for epilepsy is useful due to its neuroprotective and anti convulsive effects along with its ability to reduce stress and induce calmness. This is because of cannabidiol’s effect on the endocannabinoid system which is a network of endocannabinoids and the cannabinoid CBD is similar in function to them.
CBD due to its allosteric modulation intensifies the action of GABA receptors i.e. they induce calmness, it also reduces the activity of NMDA receptors. These compounded effects are the reason for cannabidiols anti convulsive property that is useful in the treatment of Grand Mal seizures. You should also know that the FDA has approved Epidiolex, a CBD derived drug that is used for the treatment of Dravet’s syndrome and Lennox-Gastaut syndrome. CBD oil for grand mal seizures is also useful due to these reasons.
What The Research Says?
Epilepsy is the most researched condition for which CBD’s effectiveness is studied in detail. But, more studies are conducted to identify its other potential benefits. Besides, it should be noted that Epidiolex reduced the frequency of seizures by up to 23%.
So, CBD oil for grand mal seizures is a good option due to cannabidiols proven track record in the treatment or reduction in severity of epilepsy.